PharmacyCodes



Penicilamina [INN-Spanish] en es it fr

Penicilamina [INN-Spanish] Brand names, Penicilamina [INN-Spanish] Analogs

Penicilamina [INN-Spanish] Brand Names Mixture

  • No information avaliable

Penicilamina [INN-Spanish] Chemical_Formula

C5H11NO2S

Penicilamina [INN-Spanish] RX_link

http://www.rxlist.com/cgi/generic3/penicillamine.htm

Penicilamina [INN-Spanish] fda sheet

Penicilamina_[INN-Spanish] FDA

Penicilamina [INN-Spanish] msds (material safety sheet)

Penicilamina_[INN-Spanish] MSDS

Penicilamina [INN-Spanish] Synthesis Reference

No information avaliable

Penicilamina [INN-Spanish] Molecular Weight

149.212 g/mol

Penicilamina [INN-Spanish] Melting Point

198.5 oC

Penicilamina [INN-Spanish] H2O Solubility

1.11E+005 mg/L

Penicilamina [INN-Spanish] State

Solid

Penicilamina [INN-Spanish] LogP

-2.09

Penicilamina [INN-Spanish] Dosage Forms

Capsule; Tablet

Penicilamina [INN-Spanish] Indication

For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis

Penicilamina [INN-Spanish] Pharmacology

Penicillamine is a chelating agent used in the treatment of Wilson's disease. It is also used to reduce cystine excretion in cystinuria and to treat patients with severe, active rheumatoid arthritis unresponsive to conventional therapy. Penicillamine is used as a form of immunosuppression to treat rheumatoid arthritis. It works by reducing numbers of T-lymphocytes, inhibiting macrophage function, decreasing IL-1, decreasing rheumatoid factor, and preventing collagen from cross-linking. Its use in Wilson's disease, a rare genetic disorder of copper metabolism, relies on its binding to accumulated copper and elimination through urine.

Penicilamina [INN-Spanish] Absorption

rapidly but incompletely

Penicilamina [INN-Spanish] side effects and Toxicity

No information avaliable

Penicilamina [INN-Spanish] Patient Information

No information avaliable

Penicilamina [INN-Spanish] Organisms Affected

Humans and other mammals